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Online References
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Prostrate Medical News
doctorshelp@jupiterprostategroup.org
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A New paper on the use of GM-CSF
on patients dealing with rising PSA following primary therapy was
just published in the June, 2006 edition of Urology. This drug
is commercially known as Leukine (r)and has been studied at UC-SF by
a group including Drs. Rini, Fong, Weinberg, Kavanaugh, and Small.
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Dr. Charles Myers, in
Charlottesville, VA. has used and continues to use this product in
his practice with men who experience biochemical relapse but not
metastases. He has reported success in extending the period of
non-rising PSA.
The work is quite interesting and
offers hope that this immunological approach with Leukine(r) will open
investigations into other approaches as well.
University of Alabama - Results of
Finasteride(r) PC Prevention Trials
Summary of results below courtesy of
Doctor's Guide(r):
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Urban and UAB
Division of Urology Director Anton J. Bueschen,
MD, led the UAB arm of the multicenter Prostate
Cancer Prevention Trial. The study (N Engl J
Med. 349[3]:215-224) randomized more than
18,000 men, aged 55 years and older, with a
normal DRE and PSA level of >= 3.0 ng/mL to a
daily dose of 5 mg finasteride or placebo.
Researchers had hoped finasteride, a
5a-reductase inhibitor, would reduce prostate
cancer risk.
The drug reduced by 25% the prevalence of
prostate cancer among healthy subjects, but it
increased the risk of more aggressive high-grade
tumors in patients who developed cancer.
Researchers reported "finasteride prevents or
delays the appearance of prostate cancer, but
this possible benefit and a reduced risk of
urinary problems must be weighed against sexual
side effects and increased risk of high-grade
prostate cancer."
"Further studies are needed to define future
applications for preventive medicines in
patients at high risk for prostate cancer,"
Urban says. "However, finasteride has been
proven effective for benign prostatic
hyperplasia (BPH), therefore, I do not suggest
men with BPH stop taking the drug. I explain the
study to my patients and reassure them close
follow up with PSA and DRE will detect cancer
early, if it does develop |
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Spicy Spin on Treating Prostate Cancer
WebMD Medical News,
March 15, 2006
A natural chemical in hot peppers
may become a tool in treating prostate cancer.The chemical is called
capsaicin. It puts the kick in jalapenos, habaneros, and other hot
peppers.
A study in Cancer Research shows
that capsaicin thwarted prostate cancer cells in lab tests on mice.
Capsaicin prompted cancer cells to die and curbed tumor growth, the
study shows.
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PROSTATE CANCER STEM CELLS IDENTIFIEDNewsRx.com,
February 2, 2006
Prostate cancer stem cells have
been identified. Researchers concluded, "The identification of a
prostate cancer stem cell provides a powerful tool to investigate
the tumorigenic process and to develop therapies targeted to the
stem cell."
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COMPOUNDS IN TURMERIC AND CERTAIN VEGETABLES MAY BE
EFFECTIVE AGAINST PROSTATE CANCER
NewsRx.com,
February 2, 2006
Researchers have
found that the curry spice turmeric holds real potential for the
treatment and prevention of prostate cancer, particularly when
combined with certain vegetables. The scientists tested turmeric,
also known as curcumin, along with phenethyl isothiocyanate (PEITC),
a naturally occurring substance particularly abundant in a group of
vegetables that includes watercress, cabbage, winter cress,
broccoli, Brussels sprouts, kale, cauliflower, kohlrabi, and
turnips.
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THE LOWDOWN ON PROSTATE TESTING
Manawatu Standard, January 30, 2006
This article aims to give balanced information about the PSA test,
to help you decide whether to have the test. You may wish to discuss
the issue with your doctor.
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MORE PATIENTS, BETTER OUTCOMES AFTER SURGERY FOR
UROLOGICAL CANCER
CancerConsultants.com,
01/24/2006
Patients have better outcomes after surgery for urological cancers
(such as prostate or bladder cancer) if they are treated at
hospitals or by surgeons that treat a larger number of urological
cancer patients, according to an article in
The Journal of Urology.
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